Page 344

Karger_ESC London_2013

22. European Stroke Conference 119 Stroke prognosis Clinical and imagistic short term outcome in stroke patients with early hypokalemia D. I. CUCIUREANU1, A. CUCIUREANU2 University of Medicine and Pharmacy “Gr. T. Popa” Iasi, Neurology department, Emergency Hospital “Prof.dr. N. Oblu”, IASI, ROMANIA1, CMI, IASI, ROMANIA2 Background: The aim of our study was to investigate the relationship between clinical and imagistic outcome in postischemic stroke patients with early hypokalemia. Method: We analized the clinical findings and laboratory data of 128 patients with stroke and hypokalemia, hospitalized in our neuro-logical service in the past year. All patient, aged 35 – 75, were investigated by clinical examination, dinamic brain computed tomography (admission, 3th and 5th day), blood tests, repeated electrolytes determination. Only MCA (NIHS score > 6 - < 20) infarcts and supratentorial hemorhage were anal-ised. Results: We find a direct corelation between potassium plasma concentration and augmentation of infarct volume (12 patients K⁺ <3 mEq/L: infarct volume increased at 5 days >20% - 9patients and >10% 2patients; 85 patients K⁺ > 3 mEq/l -<3,5 mEq/L: infarcts volume increased in 32 pa-tients >20% and in 18 patients >10%; 31 patients K⁺ >3,5 mEq/L - < 4 mEq/l : infarcts volume in-creased in 4 patients > 20% and in 6 patients > 10%). We also find that clinical short term outcome was dependent of potassium plasma level: K⁺ <3 mEq/L: NIHS score augmentation > 2point in 7 patients and ≤ 2 points in 3patients; K⁺ > 3 mEq/l -<3, 5 mEq/L: NIHS score augmentation > 2point in 28 patients and ≤ 2 points in 18 patients; K⁺ > 3, 5 mEq/L - < 4 mEq/ NIHS score augmentation > 2point in 2 patients and ≤ 2 points in 4 patients. Conclusion: Early low potassium plasma concentra-tion in ischemic stroke is associated with volume infarcts augmentation and poor clinical short term 344 © 2013 S. Karger AG, Basel Scientific Programme outcome. 120 Stroke prognosis RELATIONSHIP BETWEEN MIDDLE CEREBRAL ARTERY BLOOD FLOW PARAME-TERS AND CLINICAL COURSE OF THE ACUTE ISCHEMIC STROKE G. Tekgol Uzuner1, M. Baydemir2, N. Uzuner3 Eskisehir Osmangazi University, Eskisehir, TURKEY1, Eskisehir Osmangazi University, Eskise-hir, 2, Eskisehir Osmangazi University, Eskisehir, TURKEY3 Background: The aim of this study was to research whether the relationship between middle cerebral artery blood flow parameters of patients with acute ischemia of the middle cerebral artery with tran-scranial Doppler and acute, sub-acute and chronic-term clinical course. Method: Sixty-two patients with acute ischemia on the middle cerebral artery who were admitted to hospital within 12 hours after the onset of symptoms and who filled the inclusion criteria were included in the study. The transcranial Doppler was applied to patients in the acute period and their middle cerebral artery blood flow parameters were examined. Also patients were treated to a de-tailed neurological examination in acute, sub-acute and chronic periods. Results: The pulsatility index was 1.4 as measured on the lesion side. Arrival GCS value was 13.2 and NIHSS value was 12.2. In evaluations done in the sub-acute phase, the NIHSS and mRS values were 11.2 and 3.1, respectively. In neurologic examinations done in the chronic phase, the NIHSS values were 9.1 and the mRS values were 2.5. A significant negative correlation (p = 0.001) was found between pulsatility index value and the arrival GCS value (p = 0.001), and a significant posi-tive correlation was found between pulsatility index value and arrival NIHSS value (p<0.001). Also, a significant positive correlation was found between the pulsatility index value and NIHSS values in the sub-acute and chronic phase (p = 0.001 and p = 0.006 respectively) and mRS values (p = 0.001 and p = 0.004 respectively). In cases in which the PI value was larger than 1.55, the risk of death in-creased. For a good prognosis the PI might be less than or equal to 1.45 in the sub-acute phase, and less than or equal to 1.51 in controls that were performed in the chronic phase. Conclusion: It is concluded that important information can be obtained about acute, sub-acute and chronic phases of the disease course with measurement of the pulsatility index, which is an index unaffected by weaknesses in blood flow parameters measured with a transcranial Doppler, a simple method of examination in acute ischemic stroke.


Karger_ESC London_2013
To see the actual publication please follow the link above