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London, United Kingdom 2013 Detecting and reporting manifestations of SVD on neuroimaging: An international consensus statement from the centers of excellence in neurode-generation Cerebrovasc Dis 2013; 35 (suppl 3)1-854 61 (COeN) initiative Chairs: D. Leys, France and L. Pantoni, Italy Why do we need standards for vascular lesions on neuroimaging? Setting the scence M. Dichgans, Germany Proposed standards for terminology, image acquision, analysis, and reporting in research studies J. Wardlaw, UK 1 Vascular surgery and neurosurgery 9 Experimental studies A 15:50 - 16:00 Observational Study of Asymptomatic Deep Vein Thrombosis in Acute Stroke U. Ghani1, G. Muddegowda2, I. Natarajan3, C. Roffe4 University Hospital of North Stafforshire, Stoke-On-Trent, UNITED KINGDOM1,Uni-versity Hospital of North Staffordshire, Stoke-On-Trent, UNITED KINGDOM2, University Hospital of North Staffordshire, Stoke-On-Trent, UNITED KINGDOM3, University Hospital of North Staffordshire, Stoke-on-Trent, UNITED KINGDOM4 Background: Venous Thromboembolism (VTE) is a significant cause of morbidity and mortal-ity in recovery phase of acute stroke. There is no robust evidence regarding use of anticoagu-lation in prevention of deep vein thrombosis (DVT) in acute stroke as risk of symptomatic in-tracranial haemorrhage (sICH) outweighs the benefit. This observational study investigated the incidence of asymptomatic DVT and relevance of clinical and biochemical factors in patients hospitalised for 7 days in Acute Stroke Unit. Method: Plasma samples were obtained for D-dimers from 50 non-ambulatory asymptomat-ic patients for VTE after 7 days of ischaemic or haemorrhagic stroke. Samples were taken on the same day of Venous Duplex Ultrasound of both lower limbs. Analysis was done to deter-mine whether D-dimer level, age, sex, stroke syndrome, Thrombolysis, Endovascular therapy, co-morbidities, Previous Immobility, Previous VTE and ambulatory status could classify the patient’s DVT status. Results: six of 50 patients had asymptomatic DVT on duplex ultrasound. D-dimer levels fail to stratify the risk of asymptomatic DVT as they were found to vary between the range of 500 to >1000. On the other hand D-dimer levels were very high (>1000) in total anterior circulation ischaemic stroke (TACI) patients who had no DVT. 2 of the patients were bed bound haemor-rhagic stroke (TACS), 1 had recent ankle fracture, 1 had endovascular treatment for ischaemic stroke, 1 had pre-morbid modified rankin score of four because of reduced mobility and 1 had multiple co-morbidities including Atrial Fibrillation in asymptomatic DVT patients. Conclusion: 12% patients had asymptomatic DVT. D-dimer level can be falsely raised due to clot burden in acute ischaemic stroke patients. A very low value of D-dimer <250 can be used to rule out DVT.A larger study needed to further confirm these results. 16:30-17:30 Special Session Room 7,8,11,12 SVD on neuroimaging


Karger_ESC London_2013
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