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London, United Kingdom 2013 Poster Session Red Cerebrovasc Dis 2013; 35 (suppl 3)1-854 513 428 Behavioral disorders and post-stroke dementia Longitudinal assessment using domain specific cognitive tasks indicate the presence of initial subtle memory and attentional deficits and later recovery in an Irish stroke sample. J.T. Duffin1, D.R. Collins2, T.L. Coughlan3, D. O’Neill4, R.A.P. Roche5, S Commins6 Dept of psychology , National University of Ireland Maynooth., Maynooth, IRELAND1, Stroke-Service /Age Related Health Care Tallght Hospital, Dublin, IRELAND2, Stroke-Service / Age Related Health Care Tallght Hospital, Dublin, IRELAND3, Stroke-Service /Age Related Health Care Tallght Hospital, Dublin, IRELAND4, Dept of psychology , National University of Ireland Maynooth., Maynooth, IRELAND5, Dept of psychology , National University of Ireland Maynooth., Maynooth, IRELAND6 Introduction: Stroke can leave survivors with deficits in sensory, motor and cognitive systems. While sensory and motor system deficits are normally comprehensively assessed and rehabilitated, a subtle spectrum of cognitive deficits can remain inadequately assessed in non- dominant cortical strokes in the months immediately after ictus. We report a novel battery of cognitive tests and profiling to comprehensive-ly assess functions such as attention, executive function and memory. Method: Longtitudinal prospective study of consecutive non-dominant side cortical stroke patients with non-dominant parietal infarction (n=12) with matched controls (n=12) at two time intervals, T1 (Mean of 20.1 days post stroke ) and T2 6 months later . Patients consented to a battery of table-top and computer based tests of cognition. Results: stroke group :8 male and mean age 57.6 years.Control group;matched healthy participants ;8 male and mean age 57.8 years. Immediately post-stroke patients were found not to be impaired (i.e. they matched the control group performance and scores) on the general cognitive tasks including Nation-al Adult Reading Task (NART), Mini Mental State Exam (MMSE), Montreal Cognitive Assess-ment Test (MoCA) the Cognitive Failure Questionnaire (CFQ). Stroke patients also unimpaired on computer-based tasks specific to visual attention (Visual Search Task) and episodic memory (Visual Paired Associates Task). However, we found that patients were impaired on tasks for verbal (Rey Auditory Verbal Learning Test) and spatial memory (Spatial Grid Task) as well as executive func-tion (Trail Making Test), but 6 months later after rehabilitation patients showed no deficits on these tasks. Conclusion: We recommend in-depth multidomain cognitive assessment in non dominant strokes and that non-dominant cognitive deficits require in-depth assessment and monitoring to inform patient-orien-tated rehabilitation. 429 Behavioral disorders and post-stroke dementia An evaluation of treatment integrity in a multicentre randomised controlled trial of be-havioural therapy for low mood in stroke patients with aphasia (the CALM study) S.A. Thomas1, C. Russell2, R. Seed3, E. Worthington4, M.F. Walker5, J. Macniven6, N.B. Lincoln7 University of Nottingham, Nottingham, UNITED KINGDOM1, University of Nottingham, Not-tingham, UNITED KINGDOM2, University of Nottingham, Nottingham, UNITED KINGDOM3, University of Nottingham, Nottingham, UNITED KINGDOM4, University of Nottingham, Notting-ham, UNITED KINGDOM5, University of Nottingham, Nottingham, UNITED KINGDOM6, Uni-versity of Nottingham, Nottingham, UNITED KINGDOM7 Background: Studies of complex interventions in stroke rehabilitation do not often report wheth-er therapy was delivered as intended (treatment integrity). In multicentre studies it is important to check for consistency across therapists and centres. The current study evaluated the treatment integrity of the behavioural therapy intervention delivered in the Communication and Low Mood (CALM) trial. Methods: CALM trial participants were assessed on measures of language, disability and mood. Associations between levels of language, disability, mood, and the number and length of therapy sessions were assessed. Therapists delivering behavioural therapy documented session content in 10-minute units on a predefined record form. The proportion of time spent on different therapy com-ponents as therapy progressed was evaluated in relation to the treatment manual. Programme drift and differences in therapy content across centres were evaluated. Results: Forty-four patients received treatment (mean 9.1 sessions, range 3-18), with mean duration of each session 58 minutes (SD 10.7). There were no significant associations between the severity of patients’ aphasia, disability and mood problems and the length (r=-0.02-0.22, p=0.15-0.89) and number (r=-0.18-0.2, p=0.20-0.87) of therapy sessions. The amount of time spent on some therapy components significantly differed as therapy progressed (p<0.001-p=0.78). The content of therapy showed some differences between study centres (p=0.001-p=0.98). There was programme drift over the course of the study for some components of therapy (p=0.001-0.97). Conclusion: The content of therapy changed as therapy progressed, suggesting that therapists deliv-ered the intervention in accordance with the manual. As there was programme drift and differences between centres for some therapy components it is recommended that further guidance should be added to the manual and delivery of therapy is systematically monitored across therapists and cen-tres.


Karger_ESC London_2013
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