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London, United Kingdom 2013 Poster Session Blue Cerebrovasc Dis 2013; 35 (suppl 3)1-854 835 924 Interventional neurology Is the early carotid artery stenting and angioplasty for symptomatic stenosis safe?. O. Lara1, F. Moniche2, J.R. Gonzalez-Marcos3, I. Gutierrez4, J. De la Torre5, A. Cayuela6, A. May-ol7, A. Gonzalez8 Hospitales Universitarios Virgen del Rocío, Seville, SPAIN1, Hospitales Universitarios Virgen del Rocío, Seville, SPAIN2, Hospitales Universitarios Virgen del Rocío, Seville, SPAIN3, Hospitales Universitarios Virgen del Rocío, Seville, SPAIN4, Hospitales Universitarios Virgen del Rocío, Se-ville, SPAIN5, Hospitales Universitarios Virgen del Rocío, Seville, SPAIN6, Hospitales Universitari-os Virgen del Rocío, Seville, SPAIN7, Hospitales Universitarios Virgen del Rocío, Seville, SPAIN8 Background: The benefit of endarterectomy has been proven to be dependent of the timing of sur-gery in relation to the presenting TIA or stroke event. Nowadays, carotid artery stenting and angio-plasty (CAS) is an alternative of endarterectomy. However, there is uncertainty about the safety of performing CAS among patients with a recent TIA or stroke. Methods: We conducted a retrospective analysis of our prospective database of patients who under-went CAS for severe carotid stenosis since January 2002 to December 2012. Patients were classified as follows: asymptomatic patients; delayed CAS performed >2 weeks after symptoms; and early CAS performed </= 2 weeks after symptoms. Clinical and radiological features were reviewed. Outcomes were TIA/stroke or death up to 30 days after the procedure. Results: We included 906 consecutive patients. Of them, 170 (14,7%) were early CAS, 655 (56,7%) delayed CAS and 331 (28,6%) asymptomatic. Mean follow-up was 25,6 months. There was no dif-ference regarding clinical features or carotid stenosis among the three groups, except with peripheral artery disease (p=0,016). In the acute setting, there were less peri-procedural hypotension and bra-dycardia in early CAS group. The outcomes of TIA/stroke and death were not significantly different, however there was slightly more TIA in early CAS group (6,1% vs 3,8% in delayed-group and 3,1% in asymptomatic-group, p=0.3). Conclusion: Our results showed that early CAS can be considered safe when performed in symp-tomatic patients, favouring an immediate intervention after index ischemic event to avoid the high short-term risk of stroke. 925 Interventional neurology Imaging-to- Stent deployment Time Interval Is Shorter during Daytime Hours Vs. Evening Times in Endovascular Therapy for Acute Ischemic Stroke V. Nambiar1, M.A. Almekhlafi2, J. Desai3, S. Mishra4, O. Volny5, A.M. Demchuk6, M. Goyal7 University of Calgary, Calgary, CANADA1, Unviersity of Calgary - King Abdulaziz University, Calgary, 2, Unviersity of Calgary, Calgary, 3, Unviersity of Calgary, Calgary, 4, Unviersity of Cal-gary, Calgary, 5, Unviersity of Calgary, Calgary, 6, Unviersity of Calgary, Calgary, CANADA7 BACKGROUND Stentrievers can establish immediate by-pass effect by delivering blood to the ischemic tissue once the stent is deployed. A potential factor that may introduce delays in achieving a short imaging to first stentriever deployment time is the timing of the intervention. We assessed the feasibility of achieving short imaging to first stentriever deployment during the daytime hours. METHOD This is a longitudinal cohort of acute ischemic stroke patients treated with endovascu-lar therapy in our center between Jan 2011 to Dec 212. The imaging to first stentriever deployment time was defined as the time from the completion of CT angiogram to the first angiographic run that shows that the stentriever has been deployed in the target occluded artery. This time interval was compared between patients treated during the daytime hours (0700-1800 hours) vs. outside these hours. RESULTS 99 patients were analysed. The median imaging to first stentriever deployment time was 86 minutes (80.5 minutes during the daytime vs. 97 minutes outside these hours; U-test p value 0.038). The proportion of patients treated during daytime hours with imaging to first stentriev-er deployment time < 120 minutes was 86% compared to 65.8% outside these hours (Chi-square p 0.02). The proportion of patients with successful reperfusion (TICI 2b or 3) treated during the day-time was 76.7% compared to 76.9% outside daytime hours. Outcome data was available for 50 pa-tients (50%). The proportion with a favourable discharge modified Rankin Scale (mRS <3) in those with an imaging to first stentriever deployment time < 120 minutes was 65% vs. 20% in those who did not meet that time (Chi-square p 0.01). None of the patients who did not meet this target time achieved mRS score ≤ 1 compared to 55% of those with an imaging to first stentriever deployment time < 120 minutes (Chi-square p 0.002). CONCLUSIONS An imaging to first endovascular sten-triever deployment time < 120 minutes is feasible and was achieved more consistently during day-time hours. It was associated with better functional outcome.


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