22. European Stroke Conference 888 Intracerebral/subarachnoid haemorrhage and venous diseases SPONTANEOUS PARENCHYMAL INTRACEREBRAL HAEMORRHAGE: HOW OFTEN AN UNDERLYING LESION IS DIAGNOSED? O. Trabajos1, M.A. Mangas-Guijarro2, P. Martinez-Sanchez3, A. Tallón-Barranco4, E. Blanco-Vi-cente5, A. Martín-Montes6, B. Fuentes7, E. Díez-Tejedor8 Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz Uni-versity Hospital. Autónoma of Madrid University, Madrid, SPAIN1, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid University, Madrid, SPAIN2, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid University, Madrid, SPAIN3, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid University, Madrid, SPAIN4, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid Uni-versity, Madrid, SPAIN5, Department of Neurology and Stroke Center. IdiPAZ Health Research In-stitute. La Paz University Hospital. Autónoma of Madrid University, Madrid, SPAIN6, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid University, Madrid, SPAIN7, Department of Neurology and Stroke Center. IdiPAZ Health Research Institute. La Paz University Hospital. Autónoma of Madrid University, Ma-drid, 816 © 2013 S. Karger AG, Basel Scientific Programme SPAIN8 BACKGROUND: over 10% of spontaneous parenchymal intracerebral hemorrhages (SPIH) may have an underlying brain lesion that, in many cases, is suspected by the patient’s medical history or by neuroimaging. Our objective is to evaluate the frequency these brain lesions, which are not sus-pected in the initial neuroimaging, in patients with SPIH. METHODS: Observational study of patients with SPIH treated at a stroke unit during 2010. Patients were followed with serial neuroimaging, until the haemorrhage had disappeared, during 2011. Vari-ables analyzed: demographic data; vascular risk factors; clinical and laboratory data; neuroimaging findings: primary brain tumors, brain metastases, arteriovenous malformations (AVMs) and other vascular disorders. RESULTS: 78 patients, 69.2% male, mean age 72.96 (+ / - 11.7) years. Fourteen patients had intra-ventricular and 2 subarachnoid extension. Nine cases (11.5%) had a multifocal brain haemorrhage. Eleven (14.1%) cases showed the SPIH in an atypical location. Underlying lesion was observed in 4 cases and all were parenchymal AVM. The 4 cases showed the haemorrahge in an atypical location. We found no primary or metastatic tumors underlying the SPIH. The definitive etiologic diagnosis was: arterial hypertension (50%), amyloid angiopathy (21.8%), due to anticoagulant therapy (9%), MAV (5.1%) and unknown (14.1%). CONCLUSIONS: In this study the diagnosis of lesions underlying a SPIH is low and all in haemor-rhages with atypical location. The yield of serial neuroimaging in those SPIH with typical location is very low. 889 Intracerebral/subarachnoid haemorrhage and venous diseases Clinical profile and outcomes of early seizures in Asian patients with acute intracerebral hem-orrhage S.H. Chen1, M.C. Tseng2, C.D. Yang3, Y.W. Chen4 Department of Neurology, Landseed Hospital, Tao-Yuan County, TAIWAN1, Landseed Hospi-tal, Tao-Yuan County, TAIWAN2, Department of Neurosurgery, Landseed Hospital, Tao-Yuan Coun-ty, TAIWAN3, Department of Neurology, Landseed Hospital, Tao-Yuan County, TAIWAN4 Background: Seizures are one of the most common complications of stroke that might be associated with less chance of recovery and worse quality of life. We aimed to establish the incidence and clini-cal profile of post-stroke early seizure in patients with intracerebral hemorrhage (ICH). Methods: We prospectively recruited consecutive patients admitted to the Landseed hospital (a gen-eral community hospital in Taiwan with 650 beds) between 2006 and 2009 for ICH within 10 days of onset. Demographic and clinical characteristics were recorded at baseline and at discharge. Stan-dard descriptive statistical techniques were used to summarize data. Results: Of all 307 consecutive ICH patients (mean age 62±16, 72% men), 9 (3%) had seizures during acute hospitalization. Patients with seizures had higher baseline National Institutes of Health Stroke Scale (NIHSS) score (median IQR, 34 (30-35) versus 17 (7-31), p<0.001). No difference in cortical involvement of ICH was noted, 33% for patients with seizures and 15% for those without (p=0.127). Patients with seizures had higher in-hospital mortality (56% versus 23%, p=0.025). We did not have statistical power to do multivariable analysis to determine the associated factors reli-ably. Conclusion: Our findings differ from those of western studies in two clinical aspects: NIHSS score was associated with early seizure, and cortical involvement is not a predictor for early seizure in ICH. These may reflect differences in post-stroke seizure and primary ICH between Asian and West-ern populations.
Karger_ESC London_2013
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