22. European Stroke Conference 684 Acute stroke: clinical patterns and practice Acute stroke in patients with isolated Vertigo B.K. KIM1 Eulji Hospital, Seoul, SOUTH KOREA1 Background: The patients with isolated vertigo could have central or peripheral origin. Although some differential points between two exist, sometimes it is not easy to differentiate central from peripheral vestibular origin clinically. We investigated frequency of acute infarction on diffusion weighted imaging (DWI) and predictors associated with stroke in isolated vertigo. Methods: We prospectively evaluated consecutive patients who admitted neurology department with acute onset isolated vertigo, excluding BPPV. We had DWI from them. Demographics, stroke risk factors, associated symptoms and signs were reviewed. Also, locations and their vascular territories of lesion on DWI were investigated. Results: During the study period, 185 patients presented with isolated vertigo. We had DWI from 161 patients of them. Twenty three (14.3%) had acute lesions on DWI. Old age and male sex were predictors of stroke in multivariate analysis (p=0.03 and 0.02). The locations of lesions were cere-bellum in 17 patients, medulla in four, and pons in four. Cerebellar lesions were all posterior inferior cerebellar artery territory. Conclusion: 14.3% of patients with isolated vertigo had infarction on DWI. Male sex and old age were predictors of stroke in isolated vertigo. The possibility of central origin should be considered in patients with isolated vertigo and DWI might be a good diagnostic tool. 708 © 2013 S. Karger AG, Basel Scientific Programme 685 Acute stroke: clinical patterns and practice Obstructive Sleep Apnea in Acute Ischemic Stroke S.M. Rajappa1, S. Sivakumar2 Cerebrovascular and Vasculitis Research Foundation, Chennai, INDIA1, CVRF, CHENNAI, INDIA2 Aim To study the incidence of obstructive sleep apnea (OSA) in patients with recent acute ischemic stroke as compared to age and sex matched healthy control group. Methods A prospective, cohort study was performed during the years 1992-2012. Overnight polysomnogra-phy (OPSG) were performed in 108 patients with a recent ischemic stroke (72 men and 36 women; mean age ±SD, 53.8±7.2 years) and 100 healthy subjects without stroke (70 men and 30 women; mean age, 54.2.6±7.6 years). OPSG were performed within 2 days to 3 weeks after the onset acute stroke. Results OSA was found in 68% (49 out of 72) men and 58.33% (21 out of 36) women with stroke and in only 11.4% (8/70) of healthy men and 6.66% (2/30)women without stroke. (P=0.007). For men and women with stroke, the mean apnea/hypopnea index (±SE)were: 28.2±6.5 events per hour, and 29.8±6.8 events per hour, respectively. The 5 and 10 year mortality for patients with OSA and stroke were 18.5% and 34.3%. Conclusions Patients with stroke have a significantly increased incidence of OSA compared with normal age and sex matched controls. Hypoxia during OSA might have predisposed these patients to acute ischemic stroke. OSA also increases the mortality associated with stroke.
Karger_ESC London_2013
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