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London, United Kingdom 2013 Poster Session Blue Cerebrovasc Dis 2013; 35 (suppl 3)1-854 633 546 Epidemiology of stroke A 10-year prospective stroke registry in a community hospital E. Palomeras1, P. Fossas2, A. Cano3, P. Sanz4, V. Casado5, D. Muriana6 Hospital de Mataro, Mataro, SPAIN1, Hospital de Mataro, Mataro, SPAIN2, Hospital de Mataro, Mataro, SPAIN3, Hospital de Mataro, Mataro, SPAIN4, Hospital de Mataro, Mataro, SPAIN5, Hospi-tal de Mataro, Mataro, SPAIN6 Background: A prospective stroke registry leads to improved knowledge of the disease. Methods: In February-2002 a prospective stroke registry was initiated in our hospital. It includes sociodemographic data, previous diseases, clinical, topographic, etiological and prognostic data. We have analyzed the results of the first 10 years. Results: 2165 patients have been included, 54.1% male, mean age 73 years-old. The most frequent vascular risk factors have been hypertension (65.4%), dyslipidemia (40.9%) and diabetes (30.6%). NIHSS median on admission: 3 (interquartile range 1-8). Stroke subtype: 79.7% ischemic strokes, 10.9% hemorrhagic, 9.4% TIA. Among ischemic strokes, the most frequent involved territory has been MCA (46%) and etiology has been cardioembolic in 26.5%, large-vessel disease in 23.7% and small-vessel in 22.9%. Most frequent topography of hemorrhages has been lobar (47.4%), and 54.8% have been attributed to hypertension. At discharge, 60.7% of patients were able to return di-rectly to their own home and 52.7% were independent for their daily life activities (DLA). Median of in-hospital stay has been 8 days. After 3 months, 78% had returned to their house and 62.9% were independent for their DLA. In-hospital mortality has been 6.5% and after 3 months 7.4%. Conclusion: Our patients’ profile is similar to other series. The low percentage of TIA is due to the implementation of our rapid protocol assessment, avoiding in-hospital admissions. In-hospital stay length, short-term and medium term disability and mortality rates are good, if we compare them with other series. 547 Epidemiology of stroke Cut-off Points of Carotid Intima-Media Thickness for Prediction of Incidence and Mortality of Cardiovascular Disease and All-cause Mortality in Japanese Urban Cohort: The Suita Study Y. Kokubo1, M. Koga2, M. Watanabe3, K. Toyoda4, K. Nagatsuka5, Y. Miyamoto6 National Cerebral and Cardiovascular Center, Suita, JAPAN1, National Cerebral and Cardiovas-cular Center, Suita, JAPAN2, National Cerebral and Cardiovascular Center, Suita, JAPAN3, National Cerebral and Cardiovascular Center, Suita, JAPAN4, National Cerebral and Cardiovascular Center, Suita, JAPAN5, National Cerebral and Cardiovascular Center, Suita, JAPAN6 Background: Carotid atherosclerosis has been used increasingly as a subclinical marker for car-diovascular disease (CVD). However, few studies have examined the cut-off points of carotid inti-ma- media thickness (IMT) for predicting CVD incidence and mortality in a general population. Methods: We studied 5,331 Japanese individuals (mean age 55.3 years, without CVD) who com-pleted a baseline survey and carotid atherosclerosis and received follow-up through December 2010. Carotid atherosclerosis was evaluated by high-resolution ultrasonography with atherosclerotic indexes of IMT in the common carotid artery (CCA), carotid artery bulb (Bulb), and internal and external carotid arteries. We obtained death certificate files with permission to confirm mortality ac-cording to the International Classification of Death. The adjusted Cox proportional hazard ratios for CVD were calculated, when we sequentially changed the cutoff values of plaques. Results: During the follow-up, we documented 310 CVD incidents and 829 all-cause mortality (in-cluding 197 CVD mortalities). When we sequentially changed the cutoff values of maximum IMT in all areas, increased risks for CVD (incidence and mortality) and all-cause mortality were observed in those with maximum IMT equal or more than 1.4 mm and 1.3 mm. In the maximum IMT, the highest values of population attributable fractions (PAF) for incident CVD, all-cause and CVD mor-talities were 38, 20, and 30%, respectively. Those for incident CVD, and all-cause and CVD mor-talities were 33, 6, and 9% in the maximum IMT in the CCA area, respectively. Those for incident CVD, all-cause and CVD mortalities were 36, 20, and 27% in the maximum IMT in the Bulb area, respectively. Conclusions: The cut-off points of carotid IMT, especially maximum IMT equal or more than 1.4 mm and 1.3 mm, are a strong and well prediction for CDV (incidence and mortality) and all-cause mortality, respectively, in a Japanese population.


Karger_ESC London_2013
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