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22. European Stroke Conference 535 Epidemiology of stroke Trends in Activities of Daily Living (ADL) among Stroke Survivors: Analysis from the South London Stroke Register 1995-2011 K. Chattopadhyay1, A. Douiri2, A. Sheldenkar3, A.G. Rudd4, C.D.A. Wolfe5, R Chen6 Division of Health and Social Care Research, King’s College London, London, UNITED KINGDOM1, Division of Health and Social Care Research, King’s College London, London, UNITED KINGDOM2, Division of Health and Social Care Research, King’s College London, London, UNITED KINGDOM3, Division of Health & Social Care Research, King’s College Lon-don; Department of Elderly Care, St Thomas’ Hospital, Guy’s&StThomas’ NHS Foundation Trust, London, UNITED KINGDOM4, Division of Health and Social Care Research, King’s College Lon-don; NIHR Biomedical Research Centre, Guy’s and St. Thomas’ NHS Foundation Trust, London, UNITED KINGDOM5, Division of Health and Social Care Research, King’s College London, Lon-don, UNITED KINGDOM6 Background National and international acute stroke care guidelines came into effect during the last decade to improve outcomes after stroke but their impact on activities of daily living (ADL) im-provement over time is not known. To the best of knowledge, no study has examined post-stroke ADL trends over time. Methods Data from the South London Stroke Register were analysed from 1995 to 2011. At 3 months and 1 year post-stroke, basic and instrumental ADL were measured using Barthel Index (poor outcome score<15) and Frenchay Activities Index (poor outcome score<=15), respectively. Trends in poor ADL over time were examined using logistic regression analyses, after adjusting for socio-demographics, pre-stroke risk factors, stroke subtype, stroke severity and processes of acute stroke care. We also examined these trends in different socio-economic groups. Results At 3 months post-stroke, the prevalence of poor basic ADL reduced significantly from 33.4% in 1995-1998 to 25.1% in 2008-2011 (trend p<0.001) and poor instrumental ADL declined significantly from 59.8% to 53.1% (trend p=0.005). The corresponding figures at 1 year were: from 27.8% to 24.3% (trend p=0.001) and from 51.6% to 42.8% (trend p=0.004). At 3 months, significant reduction in poor ADL was observed over time in the first (least deprived) and second Index of Mul-tiple Deprivation (IMD) tertiles (trend p=0.006 and 0.001, respectively in poor basic ADL; 0.019 and 0.047, respectively in poor instrumental ADL). At 1 year, poor basic ADL declined significantly over time in the first and third IMD tertiles (trend p=0.002 and 0.043, respectively), whereas poor instrumental ADL reduced significantly only in the first IMD tertile (trend p=0.05). Conclusion ADL has improved over time among stroke survivors. This may reflect the effectiveness of acute stroke care (stroke unit care and rehabilitation). Disparities in ADL improvement still exist in different socio-economic groups and health inequality needs to be tackled. 628 © 2013 S. Karger AG, Basel Scientific Programme 536 Epidemiology of stroke Epidemiology of stroke in Stavropol region of the Russian Federation M. D. Bogatiryova1, O.A. Кlochihina, L.V. Stakhovskay3 The Russian National Research Medical University named after N.I. Pirogov, Moscow, RUS-SIAN FEDERATION1, The Russian National Research Medical University named after N.I. Pi-rogov, Moscow, RUSSIAN FEDERATION2, The Russian National Research Medical University named after N.I. Pirogov, Moscow, RUSSIAN FEDERATION3 Cerebrovascular diseases is an actual medical and social problem in Stavropol region. Background and purposes: Since 2007 the program “Improvement of medical health care for cere-brovascular disease patients” has been introduced and has been working in Stavropol region. The aim of the work was to show results of the feasible program. Methods: The stroke research was held by the method Stroke Register in according to the program “Improvement of medical health care for cerebrovascular disease patients” in Stavropol region in 2009-2010. This research was held in industrial district of the city Stavropol with the population of 182407 citizens. Epidemiological stroke parameters were counted in accordance with clinical diag-nosis of neurologists. Results: Incidence of stroke was 4.31 per 1 000 population in 2010. It is higher than in 2009 (3.14 per 1000). Probably, the increase of incidence of stroke rate is connected with the stroke diagnosis improvement. Incidence of stroke rate was higher for men (4.43 per 1000) then for women (4.10 per 1 000) in 2010. High stroke incidence parameters were registered for men and women old-er aged groups. Among patients older than 70 stroke incidence index was 24.49 per 1000 in 2009 and 25.61 per 1000 in 2010. It should be noted that Stavropol region differs from other Russian Fed-eration’s regions by the most of the population older than 70. Despite of sickness rate increase, decrease of stroke mortality rate among men and women is no-ticed. Mortality rate was 1.93 per 1000 in 2009; 1.86 per 1000 in 2010. The stroke mortality rate for women was higher (2.05 per 1000) than for men ( 1.45 per 1000) in 2010. Conclusion: Results of the study “Stroke Register” in Stavropol region are suggested to make a con-clusion that some positive changes have happened in the regard to stroke mortality. It may be asso-ciated with effective implementation of the program “Improvement of medical health care for cere-brovascular disease patients”.


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