22. European Stroke Conference 596 © 2013 S. Karger AG, Basel Scientific Programme PostPartum-36/70(51.4%) of females Infections -18/106 (12Sepsis+ 5 CSOM+1 Meningitis)(16.9%) Coagulation Disorders -6/106 OCPs-17/70(24%) 27 Intracerebral/subarachnoid haemorrhage and venous diseases Analysis of 106 patients of cerebral venous-sinus thrombosis including atypical and interesting cases- a study from India B. Sharma1, A. Panagariya2, P. Dubey3, R.B. Sannegowda4, H. Kumar5 SMS Medical College Hospital, Jaipur, INDIA1, Emeritus Professor, SMS Medical College Hos-pitals, Jaipur, Rajasthan, INDIA2, SMS Medical College, Jaipur, Rajasthan, INDIA3, SMS Medical College, Jaipur, Rajasthan, INDIA4, SMS Medical College, Jaipur, Rajasthan, INDIA5 Background: Cerebral venous sinus thrombosis (CVST) is an important cause of stroke, especially in young. CVST typically presents with headache, seizures and focal neurological deficits as a result of infarcts or intracerebral hemorrhage, but it is not unusual to find atypical clinical presentations mimicking various other neurological and neurosurgical conditions. Methods: We performed a retrospective descriptive analytical study including 106 patients with ce-rebral venous sinus thrombosis, who were admitted in the department of Neurology, SMS Medical College Hospital, Jaipur, Rajasthan, India ,from August 2011 to January 2013 , and evaluated their demographic, clinical, etiologic and radiological characteristics . Results: The most common age group was between 21-40 years of age (68.86%). 74 patients (59%) were women and 32 (41%) were men. Superior sagital sinus, with or without lateral sinuses, was the most commonly involved sinus (47.1%). The most frequent clinical manifestations were headache (86%), seizures (64.1%) and papilledema (59.4%). 51.4% of females were in post partum period and 24% women had history of intake of oral contraceptive pills. In 16.9% patients infections were the risk factor. 6 patients had coagulation disorders. Many atypical interesting cases of CVST were also noted in our study. One patient had presented with SAH. 2 cases of CVST had meningioma. 2 pa-tients with extensive CVST on imaging had only mild headache. One patient with deep CVST with unilateral thalamic infarct had only mild headache. One patient of CVST also had associated cavern-ous sinus thrombosis. One patient who presented with dementia (strategically placed) with thalamic infarct had deep CVST. 3 patients who were referred as brain tumours with thalamo-ganglionic le-sions were later diagnosed as deep CVST. Conclusion: Young women form a major proportion of our patients with CVST, most of them being either postpartum or on oral contraceptives. CVST has myriad clinical presentations and can present with atypical clinical and radiological pictures mimicking other CNS diseases and may also have a significant clinic-radiological mismatch.
Karger_ESC London_2013
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