London, United Kingdom 2013 Poster Session Red Cerebrovasc Dis 2013; 35 (suppl 3)1-854 517 435 Behavioral disorders and post-stroke dementia The effect of unilateral lesions of the basal ganglia in derivational morphology and rote verbal knowledge N. EHRLE1, S. BAKCHINE2, A. PIETON3, D. VALOIS4, M.E. JOURDAIN5, C. RENKES6, J. MACOIR7, R. BELAND8 REIMS HOSPITAL; LILLE UNIVERSITY, REIMS, FRANCE1, REIMS HOSPITAL, REIMS, FRANCE2, REIMS HOSPITAL, REIMS, FRANCE3, MONTREAL UNIVERSITY, MONTREAL, CANADA4, MONTREAL UNIVERSITY, MONTREAL, CANADA5, REIMS HOSPITAL, REIMS, FRANCE6, LAVAL UNIVERSITY, LAVAL, CANADA7, MONTREAL UNIVERSITY, MONTRE-AL, CANADA8, CANADA9 Background. A number of lesion and neuroimaging studies suggested that left subcortical structures would be involved in rote verbal knowledge, whereas the right subcortical structures would play a role in morphological processing. These studies, however, included patients with bilateral, or both cortical and subcortical lesions. Methods. We recruited 20 patients with unilateral vascular lesions circumscribed either to the left (LV)or to the right subcortical (RV) structures. These 20 patients and 20 healthy participants (HP) were tested in rote verbal knowledge and in derivational morphology. Results. Results revealed sig-nificant difference between the HP and the LV group with lower scores for the LV group in rote ver-bal knowledge. In both verb from noun (NV), and noun from verb (VN) derivational tasks, the three groups had significantly lower scores in the VN task. In both NV and VN derivations, the LV group scored significantly lower than both the HP and the RV group. The RV group had scores that were not significantly different from those of the HP group. Conclusion. We concluded that lesions circumscribed to the left basal ganglia, or the ensuing hy-poperfusion in Broca’s area, impaired rote verbal knowledge and derivational morphology whereas damages circumscribed to the contralateral regions had no effect on these language abilities. 436 Behavioral disorders and post-stroke dementia A quality improvement project looking at the implementation of a formal mood pathway in acute stroke patients B.G. Ahmed1, I. Wilkinson2, I.S. Nixon3, R. Haines4, E. Parker5, L.G.Y. Choy6 Kingston Hospital National Health Service Trust, London, UNITED KINGDOM1, Kingston Hospital National Health Service Trust, London, UNITED KINGDOM2, Kingston Hospital National Health Service Trust, London, UNITED KINGDOM3, Kingston Hospital National Health Service Trust, London, UNITED KINGDOM4, Kingston Hospital National Health Service Trust, London, UNITED KINGDOM5, Kingston Hospital National Health Service Trust, London, UNITED KING-DOM6 Mood disturbance is common post-stroke upto 30% of patients suffer with depression, many remain unrecognised and untreated.To improve detection rates the National Institute for Health & Clinical Excellence(NICE) Stroke Quality Standards recommend patients are screened within 6weeks of acute stroke to identify mood disturbance.A quality improvement project was setup to establish and improve the practice of mood assessments on the Acute Stroke Unit from Sep 2012.Previously, pa-tients’ mood was discussed on a weekly basis by the multidisciplinary team(MDT) however there was no formal assessment using a validated tool. Method Data was collected retrospectively for patients admitted and discussed at MDT meetings in Au-gust2012( N=20).A Mood Assessment Pathway was introduced in Sep 2012.In this a formal mood assessment should be completed during the patients admission using one of three validated depres-sion screening tools,depending on cognition and communication. The second part of the project analysed data from Sep to Dec 2012 (N=46) to assess compliance with the pathway. Result Pre intervention:Notes were available for 11 patients(mean age=74yrs female=36%).No patients had a formal mood assessment performed,but 10 patients (90%)had mood discussed by MDT. Post intervention:N=46 (mean age=77yrs female=72%). 57% of patients had a formal mood assess-ment. Mean time to assessment was 14 days. When assessment was not done (n=20), a reason was documented in 13(65%) patients.In 45% of these the reason was because the patient was discharged before the formal assessment was complet-ed. The mean time to discharge(12.6days) was not significantly different to time to assessment in those patients who were assessed(14days p=0.5). Conclusion Introduction of the pathway has significantly improved formal assessment of mood in stroke pa-tients. It is important to ensure systems are in place to assess mood even in patients who leave quick-ly, as they may still be at risk of depression.
Karger_ESC London_2013
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