London, United Kingdom 2013 4 Acute cerebrovascular events (ACE): TIA and minor strokes 9:00 - 9:10 Withdrawn! Cerebrovasc Dis 2013; 35 (suppl 3)1-854 101 3 Acute cerebrovascular events (ACE): TIA and minor strokes 8:50 - 9:00 Clinical-DWI mismatch among TIA patients F. Purroy1, P.E. Jiménez-Caballero2, G. Mauri-Capdevila3, M.J. Torres4, A. Gorospe5, J.M. Ramírez-Moreno6, N.P. de la Ossa7, D. Cánovas8, J. A. Arenillas9, J. M. Álvarez-Sabín10, P. Martínez-Sánchez11, J. Martí-Fàbregas12, A. Rodríguez-Campello13, R. Delgado-Mederos14, J. Masjuán15 from the PROMAPA study. Stroke Project, Cerebrovascular Diseases study Group. Spanish Neurological Society Hospital Universitari Arnau de Vilanova. UdL. IRBLlleida, Lleida, SPAIN1,Department of Neurology. Hospital San Pedro de Alcántara de Cáceres, Cáceces, SPAIN2, Hospital Universi-tari Arnau de Vilanova. UdL. IRBLlleida, Lleida, SPAIN3, Department of Neurology. Hospital Universitario Son Dureta., Palma de Mallorca, SPAIN4, Department of Neurology. Hospital Universitario Son Dureta., Palma de Mallorca, SPAIN5, Hospital Universitario Infanta Cristina de Badajoz, Badajoz, SPAIN6, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, Badalona, SPAIN7, Hospital Parc Taulí, Sabadell, SPAIN8, Hospital Clínico Universitario de Valladolid, Valladolid, SPAIN9, Hospital Universitari Vall d’Hebron, Barcelona, SPAIN10, Hospital Universitario la Paz, Ma-drid, SPAIN11, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, SPAIN12, Hospital del Mar, Barcelona, SPAIN13, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, SPAIN14, Hospital Universitario Ramón y Cajal, Madrid, SPAIN15 Objective: Diffusion-weighted magnetic resonance imaging (DWI) is a sensitive diagnostic tool for detecting acute ischemic lesions in patients with transient ischemic attacks (TIA). The usefulness of the presence or absence of DWI abnormalities in the diagnostic work-up of TIA patients still remains controversial. It would be interesting to determine the clinical-DWI mis-match (difference between clinical topography and the patterns of DWI) CDM. Methods: 463 TIA patients from the PROMAPA study and 311 TIA patients from the REGIT-ELL registry underwent DWI within 7 days of symptom onset. Clinical topography (lacunar syndrome LSand not lacunar syndrome) stablished before DWI was compared with the differ-ent patters of DWI (cortical, subcortical, scattered lesions in one arterial territory and multiple areas). Results: Diffusion-weighted images abnormalities were identified in 312 (40.3%) patients. Among them, 112 (35.8%) had LS. The distribution of DWI lesions was cortical, 72 (23.1%); subcortical, 100 (32.1); scattered lesions in one arterial territory (SPOT) 109 (34.9%); and in multiple areas 31(9.9%). We observed CDM in 26% of non LS patients with DWI abnormali-ties (25.8%) and in 56% of LS patients with DWI abnormalities (14.5%). Conclusion: Our data added evidence of the clinical utility of DWI in TIA patients. DWI changed the suspected vascular TIA localization and therefore the underlying mechanisms of transient cerebral ischemia in two of five cases with acute infarction on DWI.
Karger_ESC London_2013
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