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22. European Stroke Conference 877 Intracerebral/subarachnoid haemorrhage and venous diseases CEREBRAL VENOUS SINUS THROMBOSIS IN QATAR. CLINICAL PRESENTATION, RISK FACTORS AND MANAGEMENT A. AKHTAR1, S. KAMRAN2, G. MELIKYAN3, A. D’SOUZA4, Y. OSMAN5, Y. ZAKARIA6, A. SHEHAB7, F. IBRAHIM8, D. DELEU9 NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR1, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL COR-PORATION, DOHA, QATAR2, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MED-ICAL CORPORATION, DOHA, QATAR3, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR4, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR5, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR6, NEUROLO-GY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR7, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORATION, DOHA, QATAR8, NEUROLOGY SECTION, DEPT OF MEDICINE, HAMAD MEDICAL CORPORA-TION, DOHA, QATAR9 BACKGROUND: To analyze the clinical presentations, causes, treatment and prognosis of cerebral venous sinus thrombosis (CVST) treated in a tertiary care hospital in Qatar. METHODS: A retrospective analysis of patients with CVST treated at Hamad Medical Corporation from January 2000 to October 2012. All patients underwent investigations and neuro-imaging. We recorded the demographic, etiologic, clinical, radiologic, treatment and prognostic features. RESULTS: Sixty-four patients identified, with M:F ratio of 1.6:1. Clinical presentations were headache (100%), vomiting (90%), papilloedema (60%), seizures (44%), and focal neurologic signs (22%). Loss of consciousness found in 22%, while 14% were intubated during hospitalization. Most common eti-ology was Factor V Leiden deficiency in 11%, followed by Lupus Anticoagulant Ab deficiency and high homocysteine in 9.3%, and oral contraceptive pills in 7.8%. No cause was found in 37.5%, while 61% presented in summer months (April-September). Transverse sinus occluded in 78%, su-perior saggital 73.5%, sigmoid 69%, straight 28%, and internal jugular vein occlusion in 47%. Six (9.4%) had deep venous sinus (DVS) thrombosis, while cortical vein thrombosis found in 22%. Pure infarction found in 15 (23.5%), while hemorrhagic infarction in 25% and pure intraparenchymal bleed in 12.5%. Five (7.8%) had associated subarachnoid bleed (SAH), one subdural and another one intraventricular bleed. Seven (11%) had hydrocephalus. Treatment with warfarin was given to 92%, and 36% improved within 4-12 weeks. Three died during hospitalization, two with SAH, and third with DVS occlusion. At three months 41% had complete, 36% had partial recanalization; while 24% had no repeat imaging. Sixty-one (95%) were asymptomatic at 3 months. CONCLUSION: Predominant male gender, presentation in summer months, transverse sinus involvement and asso-ciated SAH seems more common in our study. Outcome was favorable in 95%, with 77% had com-plete or partial recanalization. 810 © 2013 S. Karger AG, Basel Scientific Programme 878 Intracerebral/subarachnoid haemorrhage and venous diseases Identification of potential kidney and liver donors among deceased intracerebral hemorrhage patients T. Sairanen1, A. Koivisto2, A.-M. Koivusalo3, S. Mustanoja4, A. Meretoja5, J. Putaala6, D. Strbian7, M. Kaste8, H. Isoniemi9, T. Tatlisumak10 Helsinki ICH Study Department of Neurology, HUCH, Helsinki, FINLAND1, Department of Neurology, HUCH, Helsinki, FINLAND2, Intensive care unit, HUCH, Helsinki, FINLAND3, Department of Neurology, HUCH, Helainki, FINLAND4, Department of Neurology, HUCH, Helsinki, FINLAND5, Depart-ment of Neurology, HUCH, Helsinki, FINLAND6, Department of Neurology, HUCH, Helsinki, FINLAND7, Department of Neurology, HUCH, Helsinki, FINLAND8, Department of Neurology, HUCH, Helsinki, FINLAND9,Department of Neurology, HUCH, Helsinki, FINLAND10 Background Patients with intracerebral hemorrhage (ICH) have a high acute death rate, but they rarely become organ donors. Our multiprofessional study team developed an algorithm to identify potential kidney and liver donors among ICH patients that at present are missed. Methods We studied retrospectively patient charts of consecutive ICH patients treated between 2005 and 2010. All ICH patients who died within 14 days of onset were assessed to find out the number of pa-tients who did not have contraindications for kidney or liver donation. Results Of the total 1013 ICH patients, 254 (25%) died within 14 days. Only 8 became actual organ donors. We identified additional 9 patients suitable for kidney donation, 11 for liver, and 31 for both. These 51 patients did not differ from the actual donors with the exception of smaller ICH lesion mean of 33.7 (33.2) vs. 89.4 (84.6) mL. In most cases (96.1%), Do-Not-Resuscitate (DNR) orders were issued early leading to refrainment from ICU care. Compared with other patients who deceased within 14 days (n=195) the potential donors were younger (mean 60.3 vs. 73.3 years) and had less often previous history of hypertension (51% vs. 71.3%; p=0.006), coronary artery disease(2.1% vs. 20.9%; p0=0.002), and atrial fibrillation (10.4% vs. 26.9%; p=0.015). The potential donors could have been differentiated from all ICH patients who survived (n=558) through out the study period by their male preponderance (54.1% vs. 70.6%; p=0.02), severe hemorrhagic strokes i.e. NIHSS of 24 (vs. 8.6) and GCS mean below 8 (vs. 13.7) in addition to frequently finding midline shift and in-traventricular extension of the hemorrhage on the admission head scan (p<0.0001 all). Conclusion A fair number of ICH patients could potentially become organ donors if in-hospital practices were reorganized. Success asks for written institutional guidelines for organ transplantation screening and training of the whole acute stroke team to reduce the number of missed organ donations


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