22. European Stroke Conference 668 Acute stroke: clinical patterns and practice Risk factors and outcomes in acute ischemic patients within 4.5 hours of time window who had rapidly improving symptoms or mild stroke and did not treat with IV rt-PA in Prasat Neuro-logical 700 © 2013 S. Karger AG, Basel Scientific Programme Institute T. Tantirittisak1, C. Anukhrorwittaya2, S. Hanchaiphiboolkul3, T. Worakijthamrongchai4 Prasat Neurological Institute, Bangkok, THAILAND1, Prasat Neurological Institute, Bangkok, THAILAND2, Prasat Neurological Institute, Bangkok, THAILAND3, Prasat Neurological Institute, Bangkok, THAILAND4 Background and Purpose: Previous studies showed that patients with mild /or rapidly improving stroke had substantial unfavorable outcome when they were not treated with iv thrombolysis. We aimed to determine the risk factors that associated with the unfavorable outcomes (mRS>2) at 3 months after stroke. Method: The medical records of acute ischemic stroke patients who came to hospital within 4.5 hours after onset and were not treated with intravenous thrombolysis at Prasat Neurological Institute from October 2007 to September 2012 were retrospectively reviewed. Demographic data, clinical information, complications and clinical outcomes were collected. Functional outcome was assessed at 3 months by using the modified Rankin Scale. Univariate and multivariate analyses were per-formed to define the risk factors of unfavorable outcome (mRS > 2). Results 115 patients (66 men and 49 women) aged 59.7 + 13.5 years were included. 22 patients (19.1%) had an unfavorable outcome including 2 patients (1.7%) were died. Using univariated anal-ysis, we found that baseline factors that associated with poor outcome were: diabetes, initial BP, initial blood sugar, baseline mRS, stroke etiology, stroke syndrome and recurrent event. In the mul-tivariable analysis, initial SBP (OR, 1.04; 95%CI, 1.01-1.07; P=0.008), baseline mRS (OR, 2.12; 95%CI, 1.09-4.15; P=0.027) and recurrent event (OR, 313.61; 95%CI, 8.67-11350.34; P=0.002) were associated with unfavorable outcome. Conclusion: Patients with mild /or rapidly improving symptom and did not receive thrombolytic treatment may become disabled. High initial systolic blood pressure, high baseline mRS and recur-rent event might predict unfavorable outcome. 669 Acute stroke: clinical patterns and practice Long-term Assessment of stroke knowledge among Nigerian children in a high risk re-source- poor community F.K. Salawu1, A. Danburam2, H. Mana3, V. Zira4 Federal Medical Centre, Yola, NIGERIA1, Federal Medical Centre, Yola, NIGERIA2, Federal Medical Centre, Yola, NIGERIA3, Federal Medical Centre, Yola, NIGERIA4 Background: stroke is Nigeria’s most common neurological disorder; public understanding of stroke is limited. Education for people with stroke and their families play an important role in adapting to life with stroke. Public misperceptions and misinformation about stroke have persisted over cen-turies. The aim of this study was to evaluate the effect of locally revised stroke recognition comic book that targeted Nigerian children aged 8-12 in a high risk community. Methods: We enrolled a cohort of 90 primary school students of an economically disadvantaged high stroke risk community into a single course of multimedia tools (cartoons, comic books and video games) (three 1-hour sessions, delivered over three consecutive days to educate children about stroke and behavioral intent to call 911 using hypothetical stroke scenarios were conducted at baseline, immediately after the intervention, and three months after the initial and only interven-tion. Baseline surveys evaluated stroke knowledge using multiple-choice questions. Only students who acknowledged participating in the initial multimedia tools survey were enrolled in the delayed posttest. Results: A total of 90 students completed both pretests and immediate posttests, and 75 students completed all 3 tests, including a 3-month delayed posttest. At pretest 26.6% correctly identified 911. At immediate posttest, stroke knowledge significantly across all items with 68% calling 911. At 3-months, stroke knowledge increased significantly from posttest for all measures except sudden headache and chest pain. Conclusion: Our findings suggest that to raise public awareness, ongoing efforts are needed using clear messages and diverse activities targeted to specific audiences through multimedia had a strong positive effect on the target group in terms of learning and retention. Such intervention incorporated into a school health education may be sufficient to maintain meaningful stroke knowledge over the long term.
Karger_ESC London_2013
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