London, United Kingdom 2013 Poster Session Blue Cerebrovasc Dis 2013; 35 (suppl 3)1-854 613 506 Epidemiology of stroke Age as a Determinant Factor for Stroke Cost under National Health Assurance System Y.H. Jung1, K.S. Lee2 Department of neurology, Chang-won Fatima Hospital, Chang-won, SOUTH KOREA1, De-partment of Neurology, Chang-won Samsung Medical Center, Chang-won, SOUTH KOREA2 Background Stroke is cost burden disease. The patterns of medical resource use and cost are different by nations, health assurance system, severity of stroke, operation, thrombolysis, and patient’s age. We evaluated the age factor that contributing the cost and utilization of medical resources in hospitalized patients with acute ischemic stroke Methods In this retrospective analysis, we evaluated the cost data on 2295 patients who were admitted from March of 2003 to December of 2011 with TIA and cerebral infarction within 7 days of onset. Pa-tients were categorized according to their age. Group 1 included less than 40 years old patients. Group 2, 40 to 49, group 3, 50 to 59, group 4, 60 to 69, group 5, 70 to 79, and group 6, more than 80. According to hospital medical cost charts, the cost and proportion of it in total cost were evaluat-ed. Results The mean age of patients was 66 years, and 51.6% were female. The total inpatient cost per stroke event was estimated to be $ 2243 (US $1 was equivalent to Korean Won 1003 according the pur-chasing power parities (PPP) of 2011 on the OECD). The cost of cerebral infarction was increased from $ 2022 in 2003 to $ 2235 in 2011 significantly (p< 0.001). The total cost of young patients, less than 40, was very high ($2444). But the cost was decreasing in 50s ($2049). And the cost is increas-ing again in 80s ($2462). The proportion of cost for treatment by staff, physical therapy was signifi-cantly higher in old patients (p<0.001), however, that of image were significantly lower (p<0.001) Conclusion The inpatient cost of stroke has been increasing annually and the cost distribution of medical re-sources also has been altered. Age is contributing factor that determine the total cost of stroke and medical resource use. 507 Epidemiology of stroke Risk factors for intracerebral haemorrhage versus ischaemic stroke in Chinese compared with White populations C.F. Tsai1, B. Thomas2, C. Sudlow3 University of Edinburgh, Edinburgh, UNITED KINGDOM1, University of Edinburgh, Edin-burgh, UNITED KINGDOM2, University of Edinburgh, Edinburgh, UNITED KINGDOM3 Background: We have recently shown a slightly higher stroke incidence, younger age of onset and higher proportion of intracerebral haemorrhage (ICH) in Chinese versus White populations. Here, we assessed the evidence for differences in frequency of stroke risk factors between ICH and isch-aemic stroke (IS) in Chinese compared with White populations. Methods: We systematically sought community- or hospital-based studies conducted since 1990 that compared frequency of risk fac-tors between ICH and IS in Chinese or in White populations. For each risk factor, we calculated study-specific and random effects pooled odds ratios (ORs) for ICH versus IS in Chinese and in Whites. We assessed heterogeneity among studies with I2 and c2 statistics. Results: We identified and included 6 studies among 35000 Chinese stroke patients, and 5 studies among 47000 White stroke patients. Mean age at stroke was lower in Chinese than White patients (mean 68 versus 72 years). Risk factors studied were hypertension, diabetes, atrial fibrillation, coronary artery disease, smoking and alcohol intake. Despite substantial heterogeneity between individual studies, pooled ORs for ICH versus IS were generally of similar size and direction in Chinese and White popula-tions. However, for ICH versus IS in Chinese patients, both hypertension (OR, 1.38; 95% CI, 1.18- 1.62) and alcohol intake (OR, 1.46; 95% CI, 1.12-1.91) were significantly more frequent, while mean age was lower (mean 62 versus 69 years). None of these differed significantly between ICH and IS in Whites. Conclusion: If real, the apparently stronger associations with hypertension and with alcohol intake for ICH versus IS in Chinese compared with Whites could shed light on mech-anisms of stroke in these different populations. However, they could be explained by chance, or by differences between populations in age or in risk factor definitions. Analyses of data from very large prospective studies in Chinese and White populations are needed.
Karger_ESC London_2013
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