London, United Kingdom 2013 Poster Session Red Cerebrovasc Dis 2013; 35 (suppl 3)1-854 511 424 Behavioral disorders and post-stroke dementia The Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) in cognitive screening after ischemic stroke - Results from the Sahlgrenska Academy Study on Ischemic Stroke Outcome P. Redfors1, C. Hofgren2, I. Eriksson3, L. Holmegaard4, H. Samuelsson5, K. Jood6 Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothen-burg, Gothenburg, SWEDEN1, Institute of Neuroscience and Physiology, the Sahlgrenska Acad-emy at University of Gothenburg, Gothenburg, SWEDEN2, Institute of Neuroscience and Physiol-ogy, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, SWEDEN3, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, SWEDEN4, Institute of Neuroscience and Physiology and Department of Psychology the Sahlgrens-ka Academy at University of Gothenburg, Gothenburg, SWEDEN5, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Gothenburg, SWEDEN6 Background- The Barrow Neurological Institute Screen for Higher Cerebral Functions (BNIS) is a sensitive, short, validated test for determining cognitive dysfunction. In the present study, we inves-tigated the utility of the BNIS in screening for cognitive dysfunction after ischemic stroke in young and middle-aged patients. Methods- The BNIS (a 50-points scale) and the Mini-Mental State Examination (MMSE, 30 points) were administered to 295 consecutive patients at 7-year follow-up within the Sahlgrenska Academy Study on Ischemic Stroke Outcome. BNIS<47 and MMSE<29 were chosen to indicate cognitive dysfunction. Results- 281 (95%) of the patients were able to complete both tests. The two test scores were highly correlated (Spearman’s rho=.65, P<0.01). However, the BNIS score and subscores were normally distributed, whereas the MMSE score and subscores showed marked ceiling effects (median and interquartile range 39 (35 to 43) and 28 (26 to 29), for total BNIS and MMSE scores respectively). Two hundred fifty-four (89%) patients had BNIS<47, of whom 77 had MMSE>29, whereas only 11 patients had BNIS>47 and MMSE<29. The BNIS subscales attention, memory, visuospatial prob-lem- solving, and awareness were most affected. In patients with MMSE>29, BNIS<47 was associat-ed with a higher modified Rankin Scale scores (P<0.01). Conclusion- The BNIS showed favourable properties in assessing cognition after stroke. With the chosen cutoff score, a high proportion of patients showed signs of cognitive dysfunction. Further validation of BNIS against neuropsychological testing and its relation to life after stroke are war-ranted.
Karger_ESC London_2013
To see the actual publication please follow the link above