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London, United Kingdom 2013 THE IBEROAMERICAN CEREBROVASCULAR DISEASES SOCIETY SIECVAND - THE EUROPEAN STROKE CONFERENCE ESC APPLICABILITY OF COLLABORATIVE INITIATIVES AND REGISTRIES IN THE IMPROVEMENT OF STROKE CARE Chairs: E. Díez-Tejedor, Spain and O. del Brutto, Ecuador Collaborative Stroke Unit Registries. An opportunity to evaluate the quality performance and to improve stroke care. K. Matz, M. Brainin, Austria Cooperative strategies to amplify stroke care efficacy beyond the hospital. A. Massaro / S. Martins, Brazil Stroke Center Networks for acute reperfusion therapies at a regional level. M. Alonso de Leciñana, Spain The impact of stroke registries in stroke management in developing countries. The SITS-SIECV Cerebrovasc Dis 2013; 35 (suppl 3)1-854 155 experience. N. Kostulas and N. Wahlgren, Sweden 18 Interventional neurology A 15:50 - 16:00 Determinants of In-stent Restenosis After Elective Carotid Artery Stenting Y. Miyazaki1, T. Mori2, T. Iwata3, Y. Takahashi4, M. Nakazaki5 Shonan Kamakura General Hospital Stroke Center, Kamakura, JAPAN1,Shonan Kamak-ura General Hospital Stroke Center, Kamakura, JAPAN2, Shonan Kamakura General Hospital Stroke Center, Kamakura, JAPAN3, Shonan Kamakura General Hospital Stroke Center, Ka-makura, JAPAN4, Shonan Kamakura General Hospital Stroke Center, Kamakura, JAPAN5 <Background and Porpose> In-stent restenosis (ISR) is an important issue in the late phase af-ter carotid artery stenting (CAS). The aim of our retrospective study was to investigate determi-nants for angiographic ISR one year after elective CAS. <Materials and Methods> Included for our analysis were patients 1) who underwent elective CAS for asymptomatic or symptomatic carotid stenosis in our institution from January 2005 to September 2012 , 2) who underwent digital subtraction angiographic (DSA) investigation one year after CAS. Angiographic ISR was defined as a stenosis of more than 50% (NASCET method). We assesed clinical features, oral medications, and radiological findings. <Results> Consecutive 216 patients underwent elective CAS for 249 lesions during the study period. Among them, 217 lesions (87%) were evaluated with one-year DSA. Median follow-up period was 363 days. ISR was detected in 14 lesions (6.5%). Residual stenosis just after CAS was greater in ISR(+) group than ISR(- ) group (median 20 % vs 10 %, p=0.078). Patients took RAS inhibitors more commonly in ISR(+) group than in ISR(-) group (78.5 % vs 53.6 %, p=0.095) and Cilostazol less commonly in ISR(+) group than in ISR(-) group (7.14 % vs 35.6 %, p<0.05). There were no significant differences between ISR(+) group and ISR(-) group in terms of age, sex, commorbidities, other medications, pre-procedure stenosis, stent type. Logistic regression analysis revealed no use of cilostazol was an independent determinant (Odds Ratio 7.37, CI 1.402 - 135.9, p<0.05). <Con-clusion> Cilostazol may reduce one-year angiographic ISR after elective CAS. 16:30-18:00 Rooms 7,8,11,12 Joint Symposium 4 ESC/SIECV


Karger_ESC London_2013
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