22. European Stroke Conference 17 Interventional neurology A 15:40 - 15:50 Results of the first 107 endovascular interventions for acute stroke at the University Hos-pital of North Staffordshire C. Roffe1, N. Ahmad2, I. Natarajan3, C. Jadun4, S. Nayak5 Keele University, Stoke-on-Trent, UNITED KINGDOM1,Stoke Stroke Research Group, Stoke-on-Trent, UNITED KINGDOM2, University Hospital of North Staffordshire, , 3, Univer-sity Hospital of North Staffordshire, Stoke-on-Trent, UNITED KINGDOM4, University Hospi-tal of North Staffordshire, Stoke-on-Trent, UNITED KINGDOM5 Introduction Endovascular treatments (EVT) have the potential to accelerate reperfusion in acute ischaemic stroke with large vessel occlusion. In the UK only a few stroke centres offer this treatment. The University Hospital of North Staffordshire (UHNS) has treated the larg-est number of cases in the UK. Results of the first 107 EVT are presented here. Methods All patients treated with EVT (intra-arterial thrombolysis, mechanical thrombectomy, both, or an attempt at intervention) for acute stroke at UHNS, Stoke-on-Trent, UK, were entered into a prospective register. Data were collected from case notes, the hospital intranet, and by contact-ing the patients directly for follow-up. Baseline demographics and clinical findings, imaging results, procedural complications, National Institutes for Health Stroke Scale (NIHSS) score after 1 week, and mortality where recorded. The modified Rankin score (mRS), was assessed by a staff member not involved in the intervention at 3 months. Results From December 2009 to January 2013 107 patients (median age 68 years, median baseline NIHSS 17, anterior circu-lation 76%, iv thrombolysis 76%, 96 patients ≥90 d from onset) were treated with EVT (throm-bectomy with or without ia lysis 86%, ia lysis alone 11%, neither 3%). Revascularisation was successful (TIMI 2 or 3) in 88%. The median time from stroke onset to successful thrombus re-trieval was 6h 34min (6h 3min for anterior and 8h 13 min) for posterior circulation occlusions). A good outcome (mRS≤2) at 90 d was achieved in 50% with a mortality of 12% and symptom-atic intracranial haemorrhage in 1% (SITS definition). Eleven per cent required intensive care (mean 2 d). Twenty-eight per cent were discharged home within 1 week (median length of stay 12 d). Conclusion Interventional treatments for acute stroke led to good clinical outcomes in 50% of patients with severe strokes. This is considerably better than the natural course of stroke with comparable severity or intravenous thrombolysis. 154 © 2013 S. Karger AG, Basel Scientific Programme
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